Douglas C. Wallace

University of Pennsylvania

Public scientific profile · Unclaimed

Built from public scholarly sources. Expertise is inferred by ScienceWe from publications and has not been confirmed by the scientist.

Top expertise

  • Mitochondrial Function and Pathology

    Strong evidence · 9 supporting papers · latest 2026

  • Cancer Immunotherapy and Biomarkers

    Strong evidence · 1 supporting paper · latest 2025

  • Cancer Cells and Metastasis

    Strong evidence · 1 supporting paper · latest 2025

  • Lung Cancer Diagnosis and Treatment

    Strong evidence · 1 supporting paper · latest 2025

  • Epigenetics and DNA Methylation

    Strong evidence · 1 supporting paper · latest 2025

  • SARS-CoV-2 and COVID-19 Research

    Strong evidence · 1 supporting paper · latest 2025

  • Sirtuins and Resveratrol in Medicine

    Strong evidence · 1 supporting paper · latest 2025

  • CRISPR and Genetic Engineering

    Strong evidence · 1 supporting paper · latest 2025

Publications (15)

  • Respiratory viral infections awaken metastatic breast cancer cells in lungs

    2025DOIPMID 40739350

  • Respiration defects limit serine synthesis required for lung cancer growth and survival

    2025DOIPMID 40817267

  • Importance of De Novo Gene Evolution to Emerging Viral Threats: The ORF10 Strain-Restricted Orphan Gene of SARS-CoV-2 Promotes Pathogenesis

    2025DOIPMID 41092398

  • A mouse model of MEPAN demonstrates a role for mitochondrial fatty acid synthesis in iron–sulfur cluster and supercomplex formation

    2025DOIPMID 41021813

  • Allotopic Expression of ND6 Restores Vision in a Mitochondrial Disease Model

    2026DOIPMID 42709484

  • Mitochondrial cardiomyopathy: bridging molecular mechanisms and clinical frontiers

    2026DOIPMID 42315930

  • Partial restoration of mitochondrial dysfunction by AAV-Ant1 protects from dilated cardiomyopathy in Ant1-/- plus mtDNA mutant mice

    2025DOIPMID 41398158

  • The succinate prodrug NV354 prevents brain lesions and late-stage motor dysfunction in mitochondrial complex I deficiency

    2026DOIPMID 41704780

  • Hepatocyte mitochondrial NAD+ content is limiting for liver regeneration

    2025DOIPMID 41266821

  • Characterization of Large-Scale Mitochondrial DNA Rearrangements Using Complementary Short- and Long-Read Sequencing Approaches

    2026DOI

  • MSeqDR PMD-VR: An Expert-Curated Virtual Registry of 11,000 Mitochondrial Disease Cases Established Through Literature Mining and Generative AI Augmentation

    2026DOIPMID 42510797

  • Combined ketone body and glutamine supplementation restores aerobic energy production in AGC1-deficient neuronal progenitors

    2025DOIPMID 41398145

  • Response to Wojcik and Fraiman

    2026DOIPMID 42307629

  • Targeting mitophagy through PINK1 splicing sensitizes myeloid malignancies to venetoclax

    2025DOI

  • Optical mapping in Black genomes: Distinct LCR22 structures and 22q11.2 deletion syndrome mechanisms

    2025DOIPMID 41137608

Organizations in sourced records

Affiliation evidence only — not confirmed current employment.

  • University of Pennsylvania

Source: OpenAlex · retrieved 2026-09-27

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