Robert E. Handsaker
Broad Institute
Public scientific profile · Unclaimed
Built from public scholarly sources. Expertise is inferred by ScienceWe from publications and has not been confirmed by the scientist.
Top expertise
Genetic Neurodegenerative Diseases
Strong evidence · 5 supporting papers · latest 2026
Genomics and Rare Diseases
Strong evidence · 4 supporting papers · latest 2024
Mitochondrial Function and Pathology
Strong evidence · 4 supporting papers · latest 2026
Genetic Associations and Epidemiology
Strong evidence · 4 supporting papers · latest 2026
RNA Research and Splicing
Strong evidence · 2 supporting papers · latest 2025
Single-cell and spatial transcriptomics
Strong evidence · 2 supporting papers · latest 2024
Genomic variations and chromosomal abnormalities
Strong evidence · 2 supporting papers · latest 2024
Receptor Mechanisms and Signaling
Strong evidence · 1 supporting paper · latest 2024
Publications (15)
Protein-altering variants at copy number-variable regions influence diverse human phenotypes
2024DOIPMID 38548989
Whole genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia
2024DOIPMID 39763555
Antisense oligonucleotide–mediated MSH3 suppression reduces somatic CAG repeat expansion in Huntington’s disease iPSC–derived striatal neurons
2025DOIPMID 39937881
Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s disease
2025DOIPMID 39824182
Concerted neuron-astrocyte gene expression declines in aging and schizophrenia
2024DOIPMID 38260461
Long somatic DNA-repeat expansion drives neurodegeneration in Huntington disease
2024DOI
A concerted neuron–astrocyte program declines in ageing and schizophrenia
2024DOIPMID 38448582
A shared DNA-repeat toxicity threshold, reached somatically at cell-type-specific rates, unites cortical and striatal neurodegeneration in Huntington’s disease
2025DOIPMID 41427302
Utility of long-read sequencing for All of Us
2024DOIPMID 38281971
Insights into the causes and consequences of DNA repeat expansions from 700,000 biobank participants
2024DOIPMID 39651202
Whole-genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia
2025DOIPMID 40886051
Insights into DNA repeat expansions among 900,000 biobank participants
2026DOIPMID 41501457
Human and bacterial genetic variation shape oral microbiomes and health
2026DOIPMID 41606319
Human and bacterial genetic variation shape oral microbiomes and health
2025DOIPMID 40236410
Common α-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease
2024DOI
Organizations in sourced records
Affiliation evidence only — not confirmed current employment.
- Broad Institute
Source: OpenAlex · retrieved 2026-09-29